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Article

GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood progenitors.

The EMBO journal - 17 Jun 2002

Kitajima Kenji, Masuhara Masaaki, Era Takumi, Enver Tariq, Nakano Toru

Abstract excerpt

GATA-2 is a zinc finger transcription factor essential for the development of hematopoiesis. While GATA-2 is generally considered to play an important role in the biology of hematopoietic stem and progenitor cells, its function within these compartments is not well understood. Here we have employed both conditional expression of GATA-2 and conditional activation of a GATA-2/estrogen receptor (ER) chimera to...

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Identifiers

PMID: 12065419
DOI: 10.1093/emboj/cdf301
PMCID: PMC126056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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