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Article

Oleate induces a myofibroblast-like phenotype in mesangial cells.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2008

Mishra Rangnath, Simonson Michael S

Abstract excerpt

OBJECTIVE: High circulating free fatty acids, commonly associated with obesity and insulin resistance, impair structure and function of the microvasculature. However, the mechanisms by which fatty acids cause microvascular remodeling are unclear. Using the mesangial cell model of microvascular pericytes, we demonstrate that the monounsaturated free fatty acid oleate induces a myofibroblast phenotype, an important...

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PMID: 18096831
DOI: 10.1161/ATVBAHA.107.157339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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