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Article

Palmitate promotes the paracrine effects of macrophages on vascular smooth muscle cells: the role of bone morphogenetic proteins.

PloS one - 1 Jan 2012

Chung Ji Hyung, Jeon Hyun Ju, Hong Sung-Yu, Lee Da Lyung, Lee Kyung Hye, Kim Soo Hyuk, Han Ye Sun, Manabe Ichiro, Miller Yury I, Lee Sang-Hak

Abstract excerpt

Saturated fatty acids are known to activate macrophages and induce vascular inflammation. Although cytokines from activated macrophage influence other vascular cells, the influence of saturated fatty acids on the paracrine effect of macrophages is not fully understood yet. Here we examined the impact of palmitate on the effect of macrophages on vascular smooth muscle cells (SMCs) and their mediators. SMCs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22363399
DOI: 10.1371/journal.pone.0029100
PMCID: PMC3283596

Genes

BMP4
BMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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