Article

Extracellular vesicles originating from steatotic hepatocytes promote hepatic stellate cell senescence via AKT/mTOR signaling

2024-05-15

Abstract excerpt

The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is increasing rapidly due to the obesity epidemic. In the inflammatory stages of MASLD (NASH), activation of hepatic stellate cells (HSCs) leads to initiation and progression of liver fibrosis. Extracellular vesicles (EVs) are released from all cell types and play an important role in intercellular communication. However, the role o...

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Literature Corpus work: 38eae045-0201-55ca-8c0c-fd5eeae3e8f2
DOI: 10.22541/au.171578817.75386990/v1

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