Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-31-5p-Modified RAW 264.7 Macrophages Affect Profibrotic Phenotype of Lymphatic Endothelial Cells In Vitro.

International journal of molecular sciences - 29 Oct 2022

Moskalik Aneta, Ratajska Anna, Majchrzak Barbara, Jankowska-Steifer Ewa, Bartkowiak Krzysztof, Bartkowiak Mateusz, Niderla-Bielińska Justyna

Abstract excerpt

Cardiac lymphatic vessel (LyV) remodeling as a contributor to heart failure has not been extensively evaluated in metabolic syndrome (MetS). Our studies have shown structural changes in cardiac LyV in MetS that contribute to the development of edema and lead to myocardial fibrosis. Tissue macrophages may affect LyV via secretion of various substances, including noncoding RNAs. The aim of the study was to evaluate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endothelial Cells
Share to Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macrophages

Share to MicroRNAs

Share to Phenotype

Share to RAW 264.7 Cells

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 36361979
DOI: 10.3390/ijms232113193
PMCID: PMC9657882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-31-5p-Modified RAW 264.7 Macrophages Affect Profibrotic Phenotype of Lymphatic Endothelial Cells In Vitro.PMID 36361979Read ↗

Macrophages and fibroblasts in cardiac fibrosis: interactions and transformationSemantic proximity Read ↗

Macrophage-Dependent Intercellular Crosstalk in Multiphenotypic Heart Failure With Preserved Ejection Fraction.Semantic proximity Read ↗

Myeloid Cell Derived IL1β Contributes to Pulmonary Vascular Remodeling in Heart Failure with Preserved Ejection FractionSemantic proximity Read ↗

MicroRNAs Control Macrophage Formation and Activation: The Inflammatory Link between Obesity and Cardiovascular DiseasesSemantic proximity Read ↗

MicroRNA-21–Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure OverloadSemantic proximity Read ↗

Cardiac tissue-resident vesicles differentially modulate anti-fibrotic phenotype by age and sex through synergistic miRNA effects.Semantic proximity Read ↗

OxLDL-Stimulated Macrophages Transmit Exosomal MicroRNA-320b to Aggravate Viability, Invasion, and Phenotype Switching via Regulating PPARGC1A-Mediated MEK/ERK Pathway in Proatherogenic Vascular Smooth Muscle Cells.Semantic proximity Read ↗

M1-like macrophage-derived exosomes suppress angiogenesis and exacerbate cardiac dysfunction in a myocardial infarction microenvironment.Semantic proximity Read ↗

Resident cardiac macrophages mediate adaptive myocardial remodeling.Semantic proximity Read ↗

A novel mRNA Lipid Nanoparticle Therapy Improves Heart Failure Phenotype and Suppresses Endothelial-Mesenchymal Transition In VitroSemantic proximity Read ↗

miR-31-5p-enriched extracellular vesicles effectively restored cardiac function after myocardial infarctionSemantic proximity Read ↗

Macrophage-Derived mir-155-Containing Exosomes Suppress Fibroblast Proliferation and Promote Fibroblast Inflammation during Cardiac InjurySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.