Article

Collagen I Exacerbates Palmitate-Induced Cell Death in HepG2 Cells via Integrin-Mediated Death

2024-08-14

Abstract excerpt

Various strategies have been employed to improve the reliability of 2D, 3D, and co-culture in vitro models of nonalcoholic fatty liver disease, including using extracellular matrix proteins, such as collagen I, to promote cell adhesion. While studies have demonstrated the significant benefits of culturing cells on collagen I, its effects on HepG2 and HepaRG cell lines after exposure to palmitate (PA) have not been...

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Literature Corpus work: f1c24915-370f-5c75-8dfe-f4e2e9ef669e
DOI: 10.20944/preprints202408.0953.v1

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