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Article

Breast-cancer stromal cells with TP53 mutations and nodal metastases.

The New England journal of medicine - 20 Dec 2007

Patocs Attila, Zhang Li, Xu Yaomin, Weber Frank, Caldes Trinidad, Mutter George L, Platzer Petra, Eng Charis

Abstract excerpt

BACKGROUND: The importance of cross-talk between a cancer and its microenvironment has been increasingly recognized. We hypothesized that mutational inactivation of the tumor-suppressor gene TP53 and genomic alterations in stromal cells of a tumor's microenvironment contribute to the clinical out...

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Identifiers

PMID: 18094375
DOI: 10.1056/NEJMoa071825

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18094375-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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