Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations.

doi:10.1093/jnci/90.15.1138

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Article

Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations.

Journal of the National Cancer Institute - 5 Aug 1998

Lakhani S R, Jacquemier J, Sloane J P, Gusterson B A, Anderson T J, van de Vijver M J, Farid L M, Venter D, Antoniou A, Storfer-Isser A, Smyth E, Steel C M, Haites N, Scott R J, Goldgar D, Neuhausen S, Daly P A, Ormiston W, McManus R, Scherneck S, Ponder B A, Ford D, Peto J, Stoppa-Lyonnet D, Bignon Y J, Struewing J P, Spurr N K, Bishop D T, Klijn J G, Devilee P, Cornelisse C J, Lasset C, Lenoir G, Barkardottir R B, Egilsson V, Hamann U, Chang-Claude J, Sobol H, Weber B, Stratton M R, Easton D F

Abstract excerpt

BACKGROUND: We have previously demonstrated that breast cancers associated with inherited BRCA1 and BRCA2 gene mutations differ from each other in their histopathologic appearances and that each of these types differs from breast cancers in patients unselected for family history (i.e., sporadic c...

Topics

Adult
Age Factors
Aged
BRCA2 Protein
Breast Neoplasms
Female
Genes, BRCA1
Humans
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multivariate Analysis

Mutation

Neoplasm Proteins

Transcription Factors

Source

Open in PubMed

Identifiers

PMID: 9701363
DOI: 10.1093/jnci/90.15.1138

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9701363-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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