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Article

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas.

Nature genetics - 1 Nov 2002

Kurose Keisuke, Gilley Kristie, Matsumoto Satoshi, Watson Peter H, Zhou Xiao-Ping, Eng Charis

Abstract excerpt

We have recently shown that loss of heterozygosity of specific markers, including those at 10q23, 17p13-p15 and 16q24, can occur in the stromal and epithelial compartments of primary invasive breast carcinomas. Here, we demonstrate high frequencies of somatic mutations in TP53 (encoding tumor pro...

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Share to Epithelium
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12379854
DOI: 10.1038/ng1013

Genes

PTEN
WFDC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12379854-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas.PMID 12379854Read ↗

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