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Article

Mediator requirement downstream of chromatin remodeling during transcriptional activation of CHA1 in yeast.

The Journal of biological chemistry - 29 Feb 2008

He Qiye, Battistella Luisa, Morse Randall H

Abstract excerpt

Mediator complex is essential for transcription by RNA polymerase II in eukaryotes. Although chromatin remodeling is an integral part of transcriptional activation at many promoters, whether Mediator is required for this function has not been determined. Here we have used the yeast CHA1 gene to study the role of Mediator in chromatin remodeling and recruitment of the transcription machinery. We show by chromatin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18093974
DOI: 10.1074/jbc.M708266200

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TBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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