Article
Testing for equality of standardized composite measures of linkage disequilibrium.
Annals of human genetics - 1 Mar 2008
Hamilton D C, Cole D E C
Abstract excerpt
We described the approximate variance for a composite measure of linkage disequilibrium (LD), which depends only on genotype frequencies and allows for departure from Hardy-Weinberg disequilibrium (Hamilton et al. 2006). Here we extend this work to allow for inferences about differences in composite LD coefficients, as we illustrate with two examples. Simulations demonstrate consistency of type I error rates...
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