Article
The effect of genotyping errors on the robustness of composite linkage disequilibrium measures.
Journal of genetics - 1 Dec 2011
Li Yu Mei, Xiang Yang
Abstract excerpt
We conclude that composite linkage disequilibrium (LD) measures be adopted in population-based LD mapping or association mapping studies since it is unaffected by Hardy-Weinberg disequilibrium. Although some properties of composite LD measures have been recently studied, the effects of genotyping errors on composite LD measures have not been examined. In this report, we derived deterministic formulas to evaluate...
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