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Article

Mucosal NOD2 expression and NF-kappaB activation in pediatric Crohn's disease.

Inflammatory bowel diseases - 1 Mar 2008

Stronati Laura, Negroni Anna, Merola Paola, Pannone Veronica, Borrelli Osvaldo, Cirulli Manuela, Annese Vito, Cucchiara Salvatore

Abstract excerpt

BACKGROUND: Recent advances in the pathogenesis of Crohn's disease (CD) have suggested that an aberrant innate immune response initiates the cascade of events leading to T-cell activation and to disease development. NOD2 protein, which is mainly expressed by innate immunity cells, appears to play...

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Source

Identifiers

PMID: 18092345
DOI: 10.1002/ibd.20332

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18092345-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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