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Article

Nod1 and Nod2 in innate immunity and human inflammatory disorders.

Biochemical Society transactions - 1 Dec 2007

Le Bourhis L, Benko S, Girardin S E

Abstract excerpt

Nod (nucleotide-binding oligomerization domain) 1 and Nod2 are intracellular PRMs (pattern-recognition molecules) of the NLR (Nod-like receptor) family. These proteins are implicated in the detection of bacterial peptidoglycan and regulate pro-inflammatory pathways in response to bacteria by inducing signalling pathways such as NF-kappaB (nuclear factor kappaB) and MAPKs (mitogen-activated protein kinases). The...

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Identifiers

PMID: 18031249
DOI: 10.1042/BST0351479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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