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Article

T cell selection and differentiation in AIDS disease: the model of HIV-discordant monozygotic twins.

Journal of biological regulators and homeostatic agents - 1 Jan 2000

Agrati C, Gioia C, Soldani F, Martini F, Antinori A, Poccia F

Abstract excerpt

The model of monozygotic twins has been repeatedly studied to control the genetic and age-specific effects on HIV disease. Focusing on this natural model, the expression of CD27/CD45RA differentiation markers and the distribution of the Vbeta TCR repertoire was analyzed on CD4+ and CD8+ T cells. In our HIV-discordant monozygotic twins, a significant reduction of naive T cells and a parallel accumulation of...

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PMID: 18088551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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