HIV, 'an evolving species'. Roles of cellular activation and co-infections.

doi:10.1016/s0306-9877(03)00147-6

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Article

HIV, 'an evolving species'. Roles of cellular activation and co-infections.

Medical hypotheses - 1 Jul 2003

Plumelle Yves

Abstract excerpt

Each small variation of the genome of a species can be preserved if it is useful for the survival of the species in a given environment. Within this framework, the finality of the biological cycle of HIV consists in a search for harmony (biological coherence) with man, which is to say a stable condition. Cellular activation appears to be the strategy developed by HIV in order to achieve this coherence. The price...

Topics

Acquired Immunodeficiency Syndrome
CD4-Positive T-Lymphocytes
Cell Membrane
Disease Progression
Evolution, Molecular
Genes, Viral
Genetic Markers
HIV
HIV Infections
HLA Antigens
Humans
Lymphocyte Activation
Mutation
Phenotype
Proviruses
Time Factors

Source

Open in PubMed

Identifiers

PMID: 12781657
DOI: 10.1016/s0306-9877(03)00147-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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