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Impact of Age and HIV Status on Immune Activation, Senescence and Apoptosis

30 Sept 2020

Abstract excerpt

Introduction: Residual immune dysfunctions, resembling those that occur during normal aging, may persist even in well-treated people with HIV (PWH), and accelerated aging has been proposed. We aimed to determine if HIV infection is an independent risk factor for T-cell immune dysfunctions including increased immune activation, senescence and apoptosis. Moreover, in PWH we aimed to identify the associations...

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Identifiers

PMID: 33117394
DOI: 10.3389/fimmu.2020.583569

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