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Article

PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status

1 Oct 2007

Abstract excerpt

OBJECTIVE AND DESIGN: PD-1 expression on HIV-specific CD8 T cells was recently reported to reflect functional exhaustion, resulting in uncontrolled HIV-1 replication. Assessing PD-1 expression on T cells may be highly relevant in T-cell immunology and vaccine monitoring. However, this requires us to gain further insights into the significance of PD-1 expression on CD8 T cells in humans. METHODS: We performed a...

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PMID: 17885290
DOI: 10.1097/qad.0b013e3282eee548

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