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Article

Altered T cell differentiation associated with loss of CD27 and CD28 in HIV infected Indian individuals

21 Jun 2011

Abstract excerpt

BACKGROUND: HIV-1 infection is associated with depletion of naïve T cell subsets and skewed T cell differentiation and maturation, leading to accumulation of T cells at intermediate and end stages of differentiation. CD27 and CD28 expression have been utilized in assessing these population subsets. METHODS: We characterized T cell subsets based on expression of CD45RA, CCR7, CD27, and CD28 and compared these...

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PMID: 21695776
DOI: 10.1002/cyto.b.20610

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