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Article

Ionizing radiation sensitivity of DNA polymerase lambda-deficient cells.

Radiation research - 1 Dec 2007

Vermeulen Christie, Bertocci Barbara, Begg Adrian C, Vens Conchita

Abstract excerpt

Ionizing radiation induces a diverse spectrum of DNA lesions, including strand breaks and oxidized bases. In mammalian cells, ionizing radiation-induced lesions are targets of non-homologous end joining, homologous recombination, and base excision repair. In vitro assays show a potential involvement of DNA polymerase lambda in non-homologous end joining and base excision repair. In this study, we investigated...

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Identifiers

PMID: 18088185
DOI: 10.1667/RR1057R.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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