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Article

High-throughput sequence-based typing strategy for HLA-DRB1 based on real-time polymerase chain reaction.

Human immunology - 1 Nov 2007

Danzer Martin, Polin Helene, Pröll Johannes, Hofer Katja, Fae Ingrid, Fischer Gottfried F, Gabriel Christian

Abstract excerpt

DNA sequencing is the gold standard for high-resolution genotyping of the highly polymorphic human leukocyte antigen (HLA) loci. In the case of hematopoietic stem cell transplantation, four-digit typing of HLA class I and II genes is indicated. We developed a group-specific, real-time polymerase chain reaction (PCR) strategy for amplification of DRB1 applying TaqMan chemistry on different real-time machines. For...

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PMID: 18082572
DOI: 10.1016/j.humimm.2007.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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