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Article

High-throughput sequence-based typing strategy for HLA-DRB1 based on real-time polymerase chain reaction.

Human immunology - 1 Nov 2007

Danzer Martin, Polin Helene, Pröll Johannes, Hofer Katja, Fae Ingrid, Fischer Gottfried F, Gabriel Christian

Abstract excerpt

DNA sequencing is the gold standard for high-resolution genotyping of the highly polymorphic human leukocyte antigen (HLA) loci. In the case of hematopoietic stem cell transplantation, four-digit typing of HLA class I and II genes is indicated. We developed a group-specific, real-time polymerase...

Topics

Alleles
Base Sequence
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Polymerase Chain Reaction
Reproducibility of Results
Sensitivity and Specificity

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 18082572
DOI: 10.1016/j.humimm.2007.10.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-18082572-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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