Support for association between the Ser205Leu polymorphism of p75(NTR) and major depressive disorder.

doi:10.1038/jhg.2011.107

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Article

Support for association between the Ser205Leu polymorphism of p75(NTR) and major depressive disorder.

Journal of human genetics - 1 Nov 2011

Fujii Takashi, Yamamoto Noriko, Hori Hiroaki, Hattori Kotaro, Sasayama Daimei, Teraishi Toshiya, Hashikura Miyako, Tatsumi Masahiko, Okamoto Nagahisa, Higuchi Teruhiko, Kunugi Hiroshi

Abstract excerpt

Altered neurotrophin functions have been implicated in major depressive disorder (MDD). Previously, we reported an association between MDD and a missense polymorphism (Ser205Leu: rs2072446) of the gene encoding the p75 neurotrophin receptor (p75(NTR)). However, contradictive negative results have also been reported. This study tried to replicate the association in an independent sample. Subjects were 668 patients...

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PMID: 21938001
DOI: 10.1038/jhg.2011.107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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