Article
No association of the G1287A polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population.
Biological & pharmaceutical bulletin - 1 Oct 2007
Inoue Kazuyuki, Itoh Kunihiko, Yoshida Keizo, Higuchi Hisashi, Kamata Mitsuhiro, Takahashi Hitoshi, Shimizu Tetsuo, Suzuki Toshio
Abstract excerpt
Norepinephrinergic neurotransmission in the central nervous system have a major impact on the symptomatology in major depressive disorder (MDD), and genetic polymorphisms of norepinephrine transporter (NET) have a possibility to be involved in susceptibility to MDD. We investigated the association of the G1287A (rs5569) polymorphism of the NET gene and susceptibility to MDD by comparing 145 major depressive...
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