Article
Association between genetic polymorphism and antidepressants in major depression: a network meta-analysis.
Pharmacogenomics - 1 Aug 2020
Du Dan, Tang Qiong, Han Qiong, Zhang Jin, Liang Xuemei, Tan Youguo, Liu Kezhi, Xiang Bo
Abstract excerpt
This network meta-analysis was conducted to compare the predictive value of eight SNPs on the efficacy of antidepressants in major depressive disorder (MDD), including 5-HTTLPR, 5HTR2A (rs6311, rs6314, rs7997012 and rs6313), 5HTR2A (rs6295), BDNF (rs6265) and 5HTTSTin2. Databases were searched for related studies published up to December 2019. A total of 16 studies were included in this study. The predictive...