Article
POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells.
Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 1996
Gan L, Xiang M, Zhou L, Wagner D S, Klein W H, Nathans J
Abstract excerpt
The three members of the Brn-3 family of POU domain transcription factors are found in highly restricted sets of central nervous system neurons. Within the retina, these factors are present only within subsets of ganglion cells. We show here that in the developing mouse retina, Brn-3b protein is...
Topics
- Animals
- Animals, Newborn
- Brain
- Cell Division
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Exons
- Genotype
- Heterozygote
- Homozygote
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nerve Fibers
- Neurons
- Optic Nerve
- Polymerase Chain Reaction
- Retina