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Article

Oncogenic H-Ras V12 promotes anchorage-independent cytokinesis in human fibroblasts

11 Dec 2007

Abstract excerpt

Cell anchorage is required for cell proliferation of untransformed cells, whereas anchorage-independent growth can be induced by oncogenes and is a hallmark of transformation. Whereas anchorage-dependent control of the progression of the G(1) phase of the cell cycle has been extensively studied, it is less clear whether and how anchorage may control other cell cycle phases and whether oncogenes may affect such...

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PMID: 18077377
DOI: 10.1073/pnas.0706609105

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