Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation

18 Jan 2008

Abstract excerpt

Hematopoietic stem cells (HSCs) are the basis of bone marrow transplantation and are attractive target cells for hematopoietic gene therapy, but these important clinical applications have been severely hampered by difficulties in ex vivo expansion of HSCs. In particular, the use of cord blood for adult transplantation is greatly limited by the number of HSCs. Previously we identified angiopoietin-like proteins...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Growth Hormone and Insulin-like Growth Factors
Share to Hematopoietic Stem Cell Transplantation
Share to Lipid metabolism and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18202223
DOI: 10.1182/blood-2007-11-122119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantationPMID 18202223Read ↗

Quantitative Analysis Reveals Expansion of Human Hematopoietic Repopulating Cells After Short-term Ex Vivo CultureSemantic proximity Read ↗

Molecular Profile and Partial Functional Analysis of Novel Endothelial Cell‐Derived Growth Factors that Regulate HematopoiesisSemantic proximity Read ↗

SCID-repopulating cell activity of human cord blood-derived CD34- cells assured by intra-bone marrow injectionSemantic proximity Read ↗

Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factorSemantic proximity Read ↗

Brief Report: A Differential Transcriptomic Profile of Ex Vivo Expanded Adult Human Hematopoietic Stem Cells Empowers Them for Engraftment Better than Their Surface Phenotype.Semantic proximity Read ↗

Stromal support augments extended long-term ex vivo expansion of hemopoietic progenitor cells.Semantic proximity Read ↗

Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID–ß2m–/– repopulating cells.Semantic proximity Read ↗

Differential long-term and multilineage engraftment potential from subfractions of human CD34 + cord blood cells transplanted into NOD/SCID miceSemantic proximity Read ↗

Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapySemantic proximity Read ↗

Highly Efficient Ex Vivo Expansion of Human Hematopoietic Stem Cells Using Delta1‐Fc Chimeric ProteinSemantic proximity Read ↗

A newly discovered class of human hematopoietic cells with SCID-repopulating activity.Semantic proximity Read ↗

Umbilical cord blood progeny cells that retain a CD34+ phenotype after ex vivo expansion have less engraftment potential than unexpanded CD34+ cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.