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Article

An extensive phenotypic characterization of the hTNFalpha transgenic mice.

BMC physiology - 10 Dec 2007

Hayward Michael D, Jones Beverly K, Saparov Arman, Hain Heather S, Trillat Anne-Cecile, Bunzel Michelle M, Corona Aaron, Li-Wang Bifang, Strenkowski Bryan, Giordano Caroline, Shen Hai, Arcamone Emily, Weidlick Jeffrey, Vilensky Maria, Tugusheva Marina, Felkner Roland H, Campbell William, Rao Yu, Grass David S, Buiakova Olesia

Abstract excerpt

BACKGROUND: Tumor necrosis factor alpha (TNFalpha) is implicated in a wide variety of pathological and physiological processes, including chronic inflammatory conditions, coronary artery disease, diabetes, obesity, and cachexia. Transgenic mice expressing human TNFalpha (hTNFalpha) have previously been described as a model for progressive rheumatoid arthritis. In this report, we describe extensive...

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Identifiers

PMID: 18070349
DOI: 10.1186/1472-6793-7-13
PMCID: PMC2222242

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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