Article
Cigarette smoke differentially modulates dendritic cell maturation and function in time.
Respiratory research - 24 Oct 2015
Givi Masoumeh Ezzati, Folkerts Gert, Wagenaar Gerry T M, Redegeld Frank A, Mortaz Esmaeil
Abstract excerpt
BACKGROUND: Dendritic cells (DCs) as professional antigen presenting cells (APCs) play a critical role in the regulation of host immune responses. DCs evolve from immature, antigen-capturing cells, to mature antigen-presenting cells. The relative contribution of DCs to cigarette smoke-induced inflammation is not well documented. In the current study, we investigated a modulatory effect of cigarette smoke extract...
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