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Article

Drug-induced liver graft toxicity caused by cytochrome P450 poor metabolism.

British journal of clinical pharmacology - 1 Mar 2008

Kóbori László, Kõhalmy Krisztina, Porrogi Pálma, Sárváry Enikõ, Gerlei Zsuzsa, Fazakas János, Nagy Péter, Járay Jenõ, Monostory Katalin

Abstract excerpt

UNLABELLED: What is already known about this subject. The activity of drug-metabolizing enzymes, primarily cytochrome P450 enzymes, can determine a patient's response to a drug. Therapeutic failure or drug toxicity in the postoperative period after liver transplantation is influenced by the drug metabolizing capacity of the graft. Dose adjustment or selection of an alternative drug, which is not a substrate for...

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Identifiers

PMID: 18070218
DOI: 10.1111/j.1365-2125.2007.03056.x
PMCID: PMC2291242

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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