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Article

Increased hospital stay and allograft dysfunction in renal transplant recipients with Cyp2c19 AA variant in SNP rs4244285.

Drug metabolism and disposition: the biological fate of chemicals - 1 Feb 2013

Bosó Virginia, Herrero María José, Bea Sergio, Galiana María, Marrero Patricia, Marqués María Remedios, Hernández Julio, Sánchez-Plumed Jaime, Poveda José Luis, Aliño Salvador F

Abstract excerpt

Pharmacogenetics correlates certain genetic variants, such as single nucleotide polymorphisms (SNPs), with blood drug levels, efficacy, and adverse effects of the treatment. Tacrolimus is mainly metabolized via CYP3A4/5, whereas CYP2C19 and CYP3A4/5 are responsible for omeprazole metabolism. Omep...

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PMID: 23175667
DOI: 10.1124/dmd.112.047977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23175667-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Increased hospital stay and allograft dysfunction in renal transplant recipients with Cyp2c19 AA variant in SNP rs4244285.PMID 23175667Read ↗

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