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Article

Early treatment suppresses the development of spike-wave epilepsy in a rat model.

Epilepsia - 1 Mar 2008

Blumenfeld Hal, Klein Joshua P, Schridde Ulrich, Vestal Matthew, Rice Timothy, Khera Davender S, Bashyal Chhitij, Giblin Kathryn, Paul-Laughinghouse Crystal, Wang Frederick, Phadke Anuradha, Mission John, Agarwal Ravi K, Englot Dario J, Motelow Joshua, Nersesyan Hrachya, Waxman Stephen G, Levin April R

Abstract excerpt

PURPOSE: Current treatments for epilepsy may control seizures, but have no known effects on the underlying disease. We sought to determine whether early treatment in a model of genetic epilepsy would reduce the severity of the epilepsy phenotype in adulthood. METHODS: We used Wistar albino Glaxo...

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Identifiers

PMID: 18070091
DOI: 10.1111/j.1528-1167.2007.01458.x
PMCID: PMC3143182

Genes

HCN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18070091-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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