Article
Reduction of epileptic spike-wave activity in WAG/Rij rats fostered by Wistar dams.
Brain research - 12 Jan 2015
Sitnikova Evgenia, Rutskova Elizaveta M, Raevsky Vladimir V
Abstract excerpt
In WAG/Rij rat genetic model of absence epilepsy, the first spike-wave discharges (EEG hallmark of absence epilepsy) are known to appear after puberty, and their incidence increases with age. WAG/Rij rats are known to have a genetic predisposition to absence epilepsy, and further development of epilepsy might be influenced by epigenetic factors. This preliminary study examined the effect of early postnatal...
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