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APOBEC3G Complexes Decrease Human Immunodeficiency Virus Type 1 Production

14 Jul 2011

Abstract excerpt

APOBEC3G (A3G) is packaged into human immunodeficiency virus type 1 (HIV-1) virions unless HIV-1 virion infectivity factor (Vif) counteracts it. Virion A3G restricts HIV-1 reverse transcription and integration in target cells. Some A3G in producer cells colocalizes with specific cytoplasmic structures, in what are called "A3G complexes" here. Functional effects of producer cell A3G complexes on HIV-1 replication...

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PMID: 21752914
DOI: 10.1128/jvi.00273-11

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APOBEC3G Complexes Decrease Human Immunodeficiency Virus Type 1 ProductionPMID 21752914Read ↗

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