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Article

MC1R variants associated susceptibility to basal cell carcinoma of skin: interaction with host factors and XRCC3 polymorphism.

International journal of cancer - 15 Apr 2008

Scherer Dominique, Bermejo Justo Lorenzo, Rudnai Peter, Gurzau Eugene, Koppova Kvetoslava, Hemminki Kari, Kumar Rajiv

Abstract excerpt

The variants within the human melanocortin 1 receptor (MC1R) gene are associated with an increased risk of different skin cancers. In this study, we genotyped by direct sequencing, 529 cases of basal cell carcinoma of the skin (BCC) and 533 healthy controls for polymorphisms in the entire MC1R gene. In addition to 10 common polymorphisms, we detected 23 rare variants in the gene. The presence of any nonsynonymous...

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Identifiers

PMID: 18067130
DOI: 10.1002/ijc.23257

Genes

XRCC3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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