Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microtubules provide directional information for core PCP function.

eLife - 14 Aug 2014

Matis Maja, Russler-Germain David A, Hu Qie, Tomlin Claire J, Axelrod Jeffrey D

Abstract excerpt

Planar cell polarity (PCP) signaling controls the polarization of cells within the plane of an epithelium. Two molecular modules composed of Fat(Ft)/Dachsous(Ds)/Four-jointed(Fj) and a 'PCP-core' including Frizzled(Fz) and Dishevelled(Dsh) contribute to polarization of individual cells. How polarity is globally coordinated with tissue axes is unresolved. Consistent with previous results, we find that the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Polarity
Share to Cytoskeleton
Share to Dishevelled Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Frizzled Receptors

Share to Microscopy, Electron, Transmission

Share to Time-Lapse Imaging

Share to Wings, Animal

Source

Open in PubMed Open full text

Identifiers

PMID: 25124458
DOI: 10.7554/eLife.02893
PMCID: PMC4151085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microtubules provide directional information for core PCP function.PMID 25124458Read ↗

Prickle/spiny-legs isoforms control the polarity of the apical microtubule network in planar cell polarity.Semantic proximity Read ↗

Planar cell polarity in Drosophila.Semantic proximity Read ↗

Drosophila Dachsous and Fat polarize actin-based protrusions over a restricted domain of the embryonic denticle field.Semantic proximity Read ↗

Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium.Semantic proximity Read ↗

Cell biology of planar polarity transmission in the Drosophila wing.Semantic proximity Read ↗

Planar polarity from flies to vertebrates.Semantic proximity Read ↗

A three-tiered mechanism for regulation of planar cell polarity.Semantic proximity Read ↗

Planar cell polarity: heading in the right direction.Semantic proximity Read ↗

Planar cell polarity signaling: the developing cell's compass.Semantic proximity Read ↗

Modeling polarity buildup and cell fate decision in the fly eye: insight into the connection between the PCP and Notch pathways.Semantic proximity Read ↗

Planar polarization of the denticle field in the Drosophila embryo: roles for Myosin II (zipper) and fringe.Semantic proximity Read ↗

Ciliary proteins link basal body polarization to planar cell polarity regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.