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Article

Redundancy of non-AUG initiators. A clever mechanism to enhance the efficiency of translation in yeast.

The Journal of biological chemistry - 24 Mar 2006

Chang Kuang-Jung, Lin Grace, Men Lee-Chung, Wang Chien-Chia

Abstract excerpt

It was recently shown that ALA1, the only alanyl-tRNA synthetase gene in Saccharomyces cerevisiae, uses two successive ACG triplets as the translation initiators for its mitochondrial form. Evidence presented here argues that the second ACG triplet not only acts as a remedial initiation site for scanning ribosomes that skip the first ACG, but also enhances the activity of the preceding initiator by providing a...

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Source

Identifiers

PMID: 16431919
DOI: 10.1074/jbc.M511265200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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