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Article

Actin -related protein 3 (Arp3) is mutated in proteinuric BUF/Mna rats.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2008

Akiyama Kiyotaka, Morita Hiroyuki, Suetsugu Shiro, Kuraba Seiko, Numata Yasuharu, Yamamoto Yoshihisa, Inui Kiyoko, Ideura Terukuni, Wakisaka Noriko, Nakano Kiyoko, Oniki Hiroaki, Takenawa Tadaomi, Matsuyama Mutsushi, Yoshimura Ashio

Abstract excerpt

The BUF/Mna strain of rat is a model of focal and segmental glomerulosclerosis (FSGS) in which a quantitative trait locus (QTL) for proteinuria, Pur1, has been identified. The aim of the present study was to identify candidates for the Pur1 gene. To narrow the Pur1 QTL, we performed fine QTL mapping and single nucleotide polymorphism (SNP) genotyping. To identify candidate genes, sequencing and gene-expression...

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PMID: 18064521
DOI: 10.1007/s00335-007-9078-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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