Article
Generation of polymorphic markers tightly linked to the thymus enlargement loci by phenotype-directed representational difference analysis.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 1998
Toyota M, Ushijima T, Suzui M, Murakumo Y, Imai K, Sugimura T, Matsuyama M
Abstract excerpt
To obtain genetic markers linked to a specific genetic locus, genomic subtraction with a DNA pool of backcross or F2 intercross animals with a specific genotype at the locus is known to be effective. To determine whether the pooling strategy is also effective for isolation of genetic markers linked to a quantitative phenotype that can potentially be controlled by multiple genetic loci, we tested the ability of...
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