Article
Exaggerated neointima formation in human C-reactive protein transgenic mice is IgG Fc receptor type I (Fc gamma RI)-dependent.
The American journal of pathology - 1 Jan 2008
Xing Dongqi, Hage Fadi G, Chen Yiu-Fai, McCrory Mark A, Feng Wenguang, Skibinski Gregory A, Majid-Hassan Erum, Oparil Suzanne, Szalai Alexander J
Abstract excerpt
Neointima formation after vascular injury is exaggerated in ovariectomized (OVX) human C-reactive protein transgenic mice (CRPtg) compared to nontransgenic mice (NTG). We tested the hypothesis that this CRP-mediated exacerbation requires IgG Fc receptors (Fc gamma Rs). OVX NTG, CRPtg, and CRPtg l...
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