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Article

No effect of C-reactive protein on early atherosclerosis in LDLR-/- / human C-reactive protein transgenic mice.

Thrombosis and haemostasis - 1 Jan 2008

Torzewski Michael, Reifenberg Kurt, Cheng Fei, Wiese Elena, Küpper Ines, Crain Jeanine, Lackner Karl J, Bhakdi Sucharit

Abstract excerpt

The association between increased concentrations of C-reactive protein (CRP) and future cardiovascular events is well established. However, it is currently unclear whether this clinical observation represents an epiphenomenon or whether the pentraxin may actively promote the development of atherosclerosis. Experimental studies with knockout mice with a defect in apolipoprotein E (ApoE(-/-)) have been used to...

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Identifiers

PMID: 18217154
DOI: 10.1160/TH07-10-0595

Genes

CRP
LDLR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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