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Article

C-reactive protein-mediated vascular injury requires complement.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2010

Hage Fadi G, Oparil Suzanne, Xing Dongqi, Chen Yiu-Fai, McCrory Mark A, Szalai Alexander J

Abstract excerpt

BACKGROUND: We previously demonstrated that vascular injury-induced neointima formation is exaggerated in human C-reactive protein (CRP) transgenic (CRPtg) compared to nontransgenic (NTG) mice. We now test the hypothesis that complement is required for this effect. METHODS AND RESULTS: CRPtg and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20339115
DOI: 10.1161/ATVBAHA.110.205377
PMCID: PMC2897052

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20339115-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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