Article
C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.
Circulation - 10 Feb 2004
Paul Antoni, Ko Kerry W S, Li Lan, Yechoor Vijay, McCrory Mark A, Szalai Alexander J, Chan Lawrence
Abstract excerpt
BACKGROUND: Plasma C-reactive protein (CRP) concentration is a strong predictor of atherosclerosis. However, to date, there is no in vivo evidence that CRP is proatherogenic. METHODS AND RESULTS: We studied the effect of human CRP transgene (tg) expression, under basal and turpentine-stimulated c...
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