Article
Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice.
Circulation - 5 Aug 2003
Danenberg Haim D, Szalai Alexander J, Swaminathan Rajesh V, Peng Lin, Chen Zhiping, Seifert Philip, Fay William P, Simon Daniel I, Edelman Elazer R
Abstract excerpt
BACKGROUND: C-reactive protein (CRP), an acute-phase reactant long considered merely an innocent bystander in the inflammatory process, is now recognized as a powerful predictor of cardiovascular events. Emerging in vitro evidence suggests that CRP may have direct proinflammatory and prothromboti...
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