Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.

doi:10.1093/hmg/ddm348

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Article

Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.

Human molecular genetics - 1 Mar 2008

Li Yonghong, Grupe Andrew, Rowland Charles, Holmans Peter, Segurado Ricardo, Abraham Richard, Jones Lesley, Catanese Joseph, Ross David, Mayo Kevin, Martinez Maribel, Hollingworth Paul, Goate Alison, Cairns Nigel J, Racette Brad A, Perlmutter Joel S, O'Donovan Michael C, Morris John C, Brayne Carol, Rubinsztein David C, Lovestone Simon, Thal Leon J, Owen Michael J, Williams Julie

Abstract excerpt

Late-onset Alzheimer's disease (LOAD) and Parkinson's disease (PD) are the most common neurodegenerative disorders and in both diseases susceptibility is known to be influenced by genes. We set out to identify novel susceptibility genes for LOAD by performing a large scale, multi-tiered association study testing 4692 single nucleotide polymorphism (SNPs). We identified a SNP within a putative transcription factor...

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Identifiers

PMID: 18063669
DOI: 10.1093/hmg/ddm348

Genes

NEDD9
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.PMID 18063669Read ↗

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