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Article

New alleles of Notch draw a blueprint for multifunctionality.

Trends in genetics : TIG - 1 Apr 2002

Arias Alfonso Martinez

Abstract excerpt

The Drosophila Notch protein is one of a family of receptors that mediate an essential and perhaps universal function in the assignation of cell fates during development. Activation of Notch by its ligand, Delta, leads to the cleavage of the intracellular domain of the receptor. This domain relocates to the nucleus, where it combines with the transcription factor Suppressor of Hairless to regulate gene...

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PMID: 11932008
DOI: 10.1016/s0168-9525(01)02635-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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