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Article

Deletion of integrin-linked kinase from skeletal muscles of mice resembles muscular dystrophy due to alpha 7 beta 1-integrin deficiency.

The American journal of pathology - 1 Dec 2007

Gheyara Ania L, Vallejo-Illarramendi Ainara, Zang Keling, Mei Lin, St-Arnaud Rene, Dedhar Shoukat, Reichardt Louis F

Abstract excerpt

Integrin-linked kinase (Ilk) is a serine/threonine kinase and an adaptor protein that links integrins to the actin cytoskeleton and to a number of signaling pathways involved in integrin action. We hypothesized that Ilk may act as an important effector of integrins in skeletal muscle, where these receptors provide a critical link between the sarcolemma and the extracellular matrix. Using the cre/lox system, we...

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Identifiers

PMID: 18055553
DOI: 10.2353/ajpath.2007.070555
PMCID: PMC2111119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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