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Article

Integrin-linked kinase – essential roles in physiology and cancer biology

17 Sept 2008

Abstract excerpt

Integrin-linked kinase (ILK) is a multifunctional intracellular effector of cell-matrix interactions and regulates many cellular processes, including growth, proliferation, survival, differentiation, migration, invasion and angiogenesis. The use of recently developed Cre-lox-driven recombination and RNA-interference technologies has enabled the evaluation of the physiological roles of ILK in several major organ...

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PMID: 18799788
DOI: 10.1242/jcs.017996

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