Article
Maintenance of multiallelic polymorphism at the MHC region.
Immunological reviews - 1 Dec 1991
Wills C
Abstract excerpt
Models that purport to explain the maintenance of MHC polymorphism must be able to explain a variety of phenomena. (1) The range of MHC allele frequencies at some of the loci is very large, with some alleles quite common and many others rare, while at others the range of allele frequencies is far narrower. (2) MHC alleles and their frequencies often have long persistence times, in some cases tens of millions of...
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