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Article

Effect of linkage disequilibrium between markers in linkage and association analyses.

Genetic epidemiology - 1 Jan 2007

Dupuis Josée, Albers Kees, Allen-Brady Kristina, Cho Kelly, Elston Robert C, Kappen Hilbert J, Tang Hua, Thomas Alun, Thomson Glenys, Tsung Eric, Yang Qiong, Zhang Weihua, Zhao Keyan, Zheng Gang, Ziegler Julie T

Abstract excerpt

Contributions to Group 17 of the Genetic Analysis Workshop 15 considered dense markers in linkage disequilibrium (LD) in the context of either linkage or association analysis. Three contributions reported on methods for modeling LD or selecting a subset of markers in linkage equilibrium to perform linkage analysis. When all markers were used without modeling LD, inflated evidence for linkage was observed when...

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Identifiers

PMID: 18046770
DOI: 10.1002/gepi.20291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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